Hypoxia‐induced pulmonary hypertension upregulates eNOS and TGF‐β contributing to sex‐linked differences in BMPR2 ( +/R899X ) mutant mice

Dysfunctional bone morphogenetic protein receptor 2 (BMPR2) and endothelial nitric oxide synthase (eNOS) have been largely implicated in the pathogenesis of pulmonary arterial hypertension (PAH); a life‐threatening cardiopulmonary disease. Although the incident of PAH is about three times higher in...

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Detalles Bibliográficos
Autores principales: Erewele, Ejehi O., Castellon, Maricela, Loya, Omar, Marshboom, Glenn, Schwartz, Andrew, Yerlioglu, Kayla, Callahan, Christopher, Chen, Jiwang, Minshall, Richard D., Oliveira, Suellen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722973/
https://www.ncbi.nlm.nih.gov/pubmed/36484056
http://dx.doi.org/10.1002/pul2.12163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722973/
https://www.ncbi.nlm.nih.gov/pubmed/36484056
http://dx.doi.org/10.1002/pul2.12163

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