Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice

Fragile X syndrome (FXS) is a neurodevelopmental disorder that is caused by the loss of Fragile X-linked mental retardation protein (FMRP), an RNA binding protein that can bind and recognize different RNA structures and regulate the target mRNAs’ translation involved in neuronal synaptic plasticity....

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Detalles Bibliográficos
Autores principales: Kim, Yujeong, Jeon, Se Jin, Gonzales, Edson Luck, Shin, Dongpil, Remonde, Chilly Gay, Ahn, TaeJin, Shin, Chan Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723111/
https://www.ncbi.nlm.nih.gov/pubmed/36470953
http://dx.doi.org/10.1038/s41598-022-25582-8

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