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Dermal open flow microperfusion for PK-based clinical bioequivalence studies of topical drug products
Topically applied drug products have experienced an extraordinary price increase in the United States, mostly due to a lack of generic products. Generic drug development is hindered by high costs and risks associated with clinical endpoint studies required to show bioequivalence (BE) of prospective...
Autores principales: | Birngruber, Thomas, Tiffner, Katrin I., Mautner, Selma I., Sinner, Frank M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723326/ https://www.ncbi.nlm.nih.gov/pubmed/36483734 http://dx.doi.org/10.3389/fphar.2022.1061178 |
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