The initiation factor 3 (IF3) residues interacting with initiator tRNA elbow modulate the fidelity of translation initiation and growth fitness in Escherichia coli

Initiation factor 3 (IF3) regulates the fidelity of bacterial translation initiation by debarring the use of non-canonical start codons or non-initiator tRNAs and prevents premature docking of the 50S ribosomal subunit to the 30S pre-initiation complex (PIC). The C-terminal domain (CTD) of IF3 can c...

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Detalles Bibliográficos
Autores principales: Singh, Jitendra, Mishra, Rishi Kumar, Ayyub, Shreya Ahana, Hussain, Tanweer, Varshney, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723500/
https://www.ncbi.nlm.nih.gov/pubmed/36399509
http://dx.doi.org/10.1093/nar/gkac1053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723500/
https://www.ncbi.nlm.nih.gov/pubmed/36399509
http://dx.doi.org/10.1093/nar/gkac1053

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