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rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation

RNA G-quadruplexes (rG4s) are RNA secondary structures, which are formed by guanine-rich sequences and have important cellular functions. Existing computational tools for rG4 prediction rely on specific sequence features and/or were trained on small datasets, without considering rG4 stability inform...

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Detalles Bibliográficos
Autores principales: Turner, Maor, Danino, Yehuda M, Barshai, Mira, Yacovzada, Nancy S, Cohen, Yahel, Olender, Tsviya, Rotkopf, Ron, Monchaud, David, Hornstein, Eran, Orenstein, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723610/
https://www.ncbi.nlm.nih.gov/pubmed/36350614
http://dx.doi.org/10.1093/nar/gkac950