Cargando…
rG4detector, a novel RNA G-quadruplex predictor, uncovers their impact on stress granule formation
RNA G-quadruplexes (rG4s) are RNA secondary structures, which are formed by guanine-rich sequences and have important cellular functions. Existing computational tools for rG4 prediction rely on specific sequence features and/or were trained on small datasets, without considering rG4 stability inform...
Autores principales: | Turner, Maor, Danino, Yehuda M, Barshai, Mira, Yacovzada, Nancy S, Cohen, Yahel, Olender, Tsviya, Rotkopf, Ron, Monchaud, David, Hornstein, Eran, Orenstein, Yaron |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723610/ https://www.ncbi.nlm.nih.gov/pubmed/36350614 http://dx.doi.org/10.1093/nar/gkac950 |
Ejemplares similares
-
BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures
por: Danino, Yehuda M, et al.
Publicado: (2023) -
G4mismatch: Deep neural networks to predict G-quadruplex propensity based on G4-seq data
por: Barshai, Mira, et al.
Publicado: (2023) -
RNA G-quadruplexes (rG4s): genomics and biological functions
por: Lyu, Kaixin, et al.
Publicado: (2021) -
microRNAs trip down memory lane
por: Yacovzada, Nancy S, et al.
Publicado: (2021) -
QUADRatlas: the RNA G-quadruplex and RG4-binding proteins database
por: Bourdon, Sébastien, et al.
Publicado: (2022)