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METTL3-mediated m(6)A modification stabilizes TERRA and maintains telomere stability

Telomeric repeat-containing RNA (TERRA) is a type of long non-coding RNA transcribed from telomeres, and it forms R-loops by invasion into telomeric DNA. Since either an excessive or inadequate number of R-loops leads to telomere instability, the TERRA levels need to be delicately modulated. In this...

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Detalles Bibliográficos
Autores principales:	Chen, Liping, Zhang, Canfeng, Ma, Wenbin, Huang, Junjiu, Zhao, Yong, Liu, Haiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723618/ https://www.ncbi.nlm.nih.gov/pubmed/36399511 http://dx.doi.org/10.1093/nar/gkac1027

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