Structural basis of direct and inverted DNA sequence repeat recognition by helix–turn–helix transcription factors

Some transcription factors bind DNA motifs containing direct or inverted sequence repeats. Preference for each of these DNA topologies is dictated by structural constraints. Most prokaryotic regulators form symmetric oligomers, which require operators with a dyad structure. Binding to direct repeats...

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Detalles Bibliográficos
Autores principales: Fernandez-Lopez, Raul, Ruiz, Raul, del Campo, Irene, Gonzalez-Montes, Lorena, Boer, D Roeland, de la Cruz, Fernando, Moncalian, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723621/
https://www.ncbi.nlm.nih.gov/pubmed/36370103
http://dx.doi.org/10.1093/nar/gkac1024

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