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High-affinity binding at quadruplex–duplex junctions: rather the rule than the exception
Quadruplex-duplex (Q–D) junctions constitute unique structural motifs in genomic sequences. Through comprehensive calorimetric as well as high-resolution NMR structural studies, Q–D junctions with a hairpin-type snapback loop coaxially stacked onto an outer G-tetrad were identified to be most effect...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723630/ https://www.ncbi.nlm.nih.gov/pubmed/36416262 http://dx.doi.org/10.1093/nar/gkac1088 |