Glucocorticoids unmask silent non-coding genetic risk variants for common diseases

Understanding the function of non-coding genomic sequence variants represents a challenge for biomedicine. Many diseases are products of gene-by-environment interactions with complex mechanisms. This study addresses these themes by mechanistic characterization of non-coding variants that influence g...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh Thanh L, Gao, Huanyao, Liu, Duan, Philips, Trudy Janice, Ye, Zhenqing, Lee, Jeong-Heon, Shi, Geng-xian, Copenhaver, Kaleigh, Zhang, Lingxin, Wei, Lixuan, Yu, Jia, Zhang, Huan, Barath, Abhijeet, Luong, Maggie, Zhang, Cheng, Gaspar-Maia, Alexandre, Li, Hu, Wang, Liewei, Ordog, Tamas, Weinshilboum, Richard M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723631/
https://www.ncbi.nlm.nih.gov/pubmed/36399508
http://dx.doi.org/10.1093/nar/gkac1045

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