In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation

The transition of the 90S to the pre-40S pre-ribosome is a decisive step in eukaryotic small subunit biogenesis leading to a first pre-40S intermediate (state Dis-C or primordial pre-40S), where the U3 snoRNA keeps the nascent 18S rRNA locally immature. We in vitro reconstitute the ATP-dependent U3...

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Detalles Bibliográficos
Autores principales: Cheng, Jingdong, La Venuta, Giuseppe, Lau, Benjamin, Berninghausen, Otto, Beckmann, Roland, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723636/
https://www.ncbi.nlm.nih.gov/pubmed/36263816
http://dx.doi.org/10.1093/nar/gkac910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723636/
https://www.ncbi.nlm.nih.gov/pubmed/36263816
http://dx.doi.org/10.1093/nar/gkac910

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