Cargando…
In vitro structural maturation of an early stage pre-40S particle coupled with U3 snoRNA release and central pseudoknot formation
The transition of the 90S to the pre-40S pre-ribosome is a decisive step in eukaryotic small subunit biogenesis leading to a first pre-40S intermediate (state Dis-C or primordial pre-40S), where the U3 snoRNA keeps the nascent 18S rRNA locally immature. We in vitro reconstitute the ATP-dependent U3...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723636/ https://www.ncbi.nlm.nih.gov/pubmed/36263816 http://dx.doi.org/10.1093/nar/gkac910 |