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Structural insights into target DNA recognition and cleavage by the CRISPR-Cas12c1 system

Cas12c is the recently characterized dual RNA-guided DNase effector of type V-C CRISPR-Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) systems. Due to minimal requirements for a protospacer adjacent motif (PAM), Cas12c is an attractive candidate for geno...

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Detalles Bibliográficos
Autores principales:	Zhang, Bo, Lin, Jinying, Perčulija, Vanja, Li, Yu, Lu, Qiuhua, Chen, Jing, Ouyang, Songying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723637/ https://www.ncbi.nlm.nih.gov/pubmed/36321657 http://dx.doi.org/10.1093/nar/gkac987

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