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Estrogen regulates divergent transcriptional and epigenetic cell states in breast cancer

Breast cancers are known to be driven by the transcription factor estrogen receptor and its ligand estrogen. While the receptor's cis-binding elements are known to vary between tumors, heterogeneity of hormone signaling at a single-cell level is unknown. In this study, we systematically tracked...

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Detalles Bibliográficos
Autores principales: Ors, Aysegul, Chitsazan, Alex Daniel, Doe, Aaron Reid, Mulqueen, Ryan M, Ak, Cigdem, Wen, Yahong, Haverlack, Syber, Handu, Mithila, Naldiga, Spandana, Saldivar, Joshua C, Mohammed, Hisham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723652/
https://www.ncbi.nlm.nih.gov/pubmed/36318267
http://dx.doi.org/10.1093/nar/gkac908