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Signal sequences encode information for protein folding in the endoplasmic reticulum

One-third of newly synthesized proteins in mammals are translocated into the endoplasmic reticulum (ER) through the Sec61 translocon. How protein translocation coordinates with chaperone availability in the ER to promote protein folding remains unclear. We find that marginally hydrophobic signal seq...

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Detalles Bibliográficos
Autores principales:	Sun, Sha, Li, Xia, Mariappan, Malaiyalam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723807/ https://www.ncbi.nlm.nih.gov/pubmed/36459117 http://dx.doi.org/10.1083/jcb.202203070

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