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Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study
OBJECTIVES: To examine the survival rate and predictors of mortality among preterm neonates in the neonatal intensive care unit at South Gondar public hospitals, 2021. DESIGN: Prospective follow-up study. SETTING: South Gondar public hospitals, Northwest, Ethiopia. PARTICIPANTS: We recruited 283 pre...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723894/ https://www.ncbi.nlm.nih.gov/pubmed/36576181 http://dx.doi.org/10.1136/bmjopen-2022-061385 |
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author | Chanie, Ermias Sisay Engedaw, Destaw Eyayu, Tahir Admasu, Fitalew Tadele Amera, Eninur Dejen Azanaw, Kefyalew Amogne Kassaw, Amare Feleke, Dejen Getaneh Ayehu, Gashaw Walle Jimma, Melkamu Senbeta GebreEyesus, Fisha Alebel Moges, Natnael Woelile, Tamiru Alene Kerebeh, Gashaw Birrie, Endalk |
author_facet | Chanie, Ermias Sisay Engedaw, Destaw Eyayu, Tahir Admasu, Fitalew Tadele Amera, Eninur Dejen Azanaw, Kefyalew Amogne Kassaw, Amare Feleke, Dejen Getaneh Ayehu, Gashaw Walle Jimma, Melkamu Senbeta GebreEyesus, Fisha Alebel Moges, Natnael Woelile, Tamiru Alene Kerebeh, Gashaw Birrie, Endalk |
author_sort | Chanie, Ermias Sisay |
collection | PubMed |
description | OBJECTIVES: To examine the survival rate and predictors of mortality among preterm neonates in the neonatal intensive care unit at South Gondar public hospitals, 2021. DESIGN: Prospective follow-up study. SETTING: South Gondar public hospitals, Northwest, Ethiopia. PARTICIPANTS: We recruited 283 preterm neonates who were admitted at neonatal intensive care unit at selected hospitals from 15 February 2020 to 22 January 2021. OUTCOME MEASURES: The primary outcome measure of this study was the survival rate of preterm neonates in the neonatal intensive care unit. Moreover, the study assessed the predictors for the occurrence of mortality by the Cox-proportional hazard model. Data were entered into Epi data V.4.2 and exported to Stata V.14 statistical software for analysis. The log-rank test determines the survival difference between predictor variables. RESULTS: A total of 283 preterm neonates, 61 died during the follow-up. Born from antepartum haemorrhage mother (adjusted HR (AHR)=2.2 (95% CI 1.10 to 4.37)), being small weight for gestational age (AHR=4.6 (95% CI 2.22 to 9.53)), not having kangaroo mother care practice initiated (AHR=2.7 (95% CI 1.39 to 7.74)), hypothermia (AHR=4.0 (95% CI 1.96 to 8.30)) and perinatal asphyxia (AHR=3.9 (95% CI 1.97 to 7.94)) were significant predictors of preterm neonate mortality. CONCLUSION: In this study, the preterm neonates survival rate (78.4%) and the median survival time (21 days) were found to be low. Preventing and managing the predictors, including an antepartum haemorrhagic mother, small weight for gestational age, hypothermia and prenatal asphyxia, is crucial. In addition, more emphasis should be placed on initiating universal kangaroo mother care practice soon after birth to increase the survival of preterm neonates. |
format | Online Article Text |
id | pubmed-9723894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-97238942022-12-07 Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study Chanie, Ermias Sisay Engedaw, Destaw Eyayu, Tahir Admasu, Fitalew Tadele Amera, Eninur Dejen Azanaw, Kefyalew Amogne Kassaw, Amare Feleke, Dejen Getaneh Ayehu, Gashaw Walle Jimma, Melkamu Senbeta GebreEyesus, Fisha Alebel Moges, Natnael Woelile, Tamiru Alene Kerebeh, Gashaw Birrie, Endalk BMJ Open Intensive Care OBJECTIVES: To examine the survival rate and predictors of mortality among preterm neonates in the neonatal intensive care unit at South Gondar public hospitals, 2021. DESIGN: Prospective follow-up study. SETTING: South Gondar public hospitals, Northwest, Ethiopia. PARTICIPANTS: We recruited 283 preterm neonates who were admitted at neonatal intensive care unit at selected hospitals from 15 February 2020 to 22 January 2021. OUTCOME MEASURES: The primary outcome measure of this study was the survival rate of preterm neonates in the neonatal intensive care unit. Moreover, the study assessed the predictors for the occurrence of mortality by the Cox-proportional hazard model. Data were entered into Epi data V.4.2 and exported to Stata V.14 statistical software for analysis. The log-rank test determines the survival difference between predictor variables. RESULTS: A total of 283 preterm neonates, 61 died during the follow-up. Born from antepartum haemorrhage mother (adjusted HR (AHR)=2.2 (95% CI 1.10 to 4.37)), being small weight for gestational age (AHR=4.6 (95% CI 2.22 to 9.53)), not having kangaroo mother care practice initiated (AHR=2.7 (95% CI 1.39 to 7.74)), hypothermia (AHR=4.0 (95% CI 1.96 to 8.30)) and perinatal asphyxia (AHR=3.9 (95% CI 1.97 to 7.94)) were significant predictors of preterm neonate mortality. CONCLUSION: In this study, the preterm neonates survival rate (78.4%) and the median survival time (21 days) were found to be low. Preventing and managing the predictors, including an antepartum haemorrhagic mother, small weight for gestational age, hypothermia and prenatal asphyxia, is crucial. In addition, more emphasis should be placed on initiating universal kangaroo mother care practice soon after birth to increase the survival of preterm neonates. BMJ Publishing Group 2022-12-05 /pmc/articles/PMC9723894/ /pubmed/36576181 http://dx.doi.org/10.1136/bmjopen-2022-061385 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Intensive Care Chanie, Ermias Sisay Engedaw, Destaw Eyayu, Tahir Admasu, Fitalew Tadele Amera, Eninur Dejen Azanaw, Kefyalew Amogne Kassaw, Amare Feleke, Dejen Getaneh Ayehu, Gashaw Walle Jimma, Melkamu Senbeta GebreEyesus, Fisha Alebel Moges, Natnael Woelile, Tamiru Alene Kerebeh, Gashaw Birrie, Endalk Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title | Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title_full | Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title_fullStr | Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title_full_unstemmed | Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title_short | Escalating the limit of median survival time and predictors of mortality among preterm neonates in Northwest Ethiopia, 2021: a 1-year prospective follow-up study |
title_sort | escalating the limit of median survival time and predictors of mortality among preterm neonates in northwest ethiopia, 2021: a 1-year prospective follow-up study |
topic | Intensive Care |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723894/ https://www.ncbi.nlm.nih.gov/pubmed/36576181 http://dx.doi.org/10.1136/bmjopen-2022-061385 |
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