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Phosphatidylserine exposure modulates adhesion GPCR BAI1 (ADGRB1) signaling activity

Brain-specific angiogenesis inhibitor 1 (BAI1; also called ADGRB1 or B1) is an adhesion G protein–coupled receptor known from studies on macrophages to bind to phosphatidylserine (PS) on apoptotic cells via its N-terminal thrombospondin repeats. A separate body of work has shown that B1 regulates po...

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Detalles Bibliográficos
Autores principales: Lala, Trisha, Doan, Juleva K., Takatsu, Hiroyuki, Hartzell, H. Criss, Shin, Hye-Won, Hall, Randy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723945/
https://www.ncbi.nlm.nih.gov/pubmed/36370845
http://dx.doi.org/10.1016/j.jbc.2022.102685

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