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Anti-CD73 antibody activates human B cells, enhances humoral responses and induces redistribution of B cells in patients with cancer

BACKGROUND: CD73 is widely expressed on immune cells playing a critical role in immunomodulatory functions including cell adhesion and migration, as a costimulatory molecule for T cells and in production of adenosine. The function of CD73 expressed on B cells has not been fully characterized. Mupado...

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Detalles Bibliográficos
Autores principales:	Miller, Richard A, Luke, Jason John, Hu, Shenshen, Mahabhashyam, Suresh, Jones, William B, Marron, Thomas, Merchan, Jaime R, Hughes, Brett G M, Willingham, Stephen B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Clinical/Translational Cancer Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723961/ https://www.ncbi.nlm.nih.gov/pubmed/36600561 http://dx.doi.org/10.1136/jitc-2022-005802

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