One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate

[Image: see text] The efficient asymmetric catalytic synthesis of amines containing more than one stereogenic center is a current challenge. Here, we present a biocatalytic cascade that combines ene-reductases (EReds) with imine reductases/reductive aminases (IReds/RedAms) to enable the conversion o...

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Detalles Bibliográficos
Autores principales: Knaus, Tanja, Corrado, Maria L., Mutti, Francesco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724091/
https://www.ncbi.nlm.nih.gov/pubmed/36504913
http://dx.doi.org/10.1021/acscatal.2c03052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724091/
https://www.ncbi.nlm.nih.gov/pubmed/36504913
http://dx.doi.org/10.1021/acscatal.2c03052

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