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One-Pot Biocatalytic Synthesis of Primary, Secondary, and Tertiary Amines with Two Stereocenters from α,β-Unsaturated Ketones Using Alkyl-Ammonium Formate

[Image: see text] The efficient asymmetric catalytic synthesis of amines containing more than one stereogenic center is a current challenge. Here, we present a biocatalytic cascade that combines ene-reductases (EReds) with imine reductases/reductive aminases (IReds/RedAms) to enable the conversion o...

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Detalles Bibliográficos
Autores principales:	Knaus, Tanja, Corrado, Maria L., Mutti, Francesco G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724091/ https://www.ncbi.nlm.nih.gov/pubmed/36504913 http://dx.doi.org/10.1021/acscatal.2c03052

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