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USP44 accelerates the growth of T-cell acute lymphoblastic leukemia through interacting with WDR5 and repressing its ubiquitination

T-cell acute lymphoblastic leukemia (T-ALL) is a common hematologic malignancy. Based on the data from GSE66638 and GSE141140, T-ALL patients depicted a higher USP44 level. However, its role in T-ALL is still unclear. In the present study, we investigated the role of USP44 in T-ALL growth. USP44 ove...

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Detalles Bibliográficos
Autores principales: Chi, Zuofei, Zhang, Bin, Sun, Ruowen, Wang, Ye, Zhang, Linlin, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724245/
https://www.ncbi.nlm.nih.gov/pubmed/36483601
http://dx.doi.org/10.7150/ijms.74535

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