Blockade of SK4 channels suppresses atrial fibrillation by attenuating atrial fibrosis in canines with prolonged atrial pacing

Background: We previously found that intermediate conductance Ca(2+)-activated K(+) channel (SK4) might be an important target in atrial fibrillation (AF). Objective: To investigate the role of SK4 in AF maintenance. Methods: Twenty beagles were randomly assigned to the sham group (n=6), pacing grou...

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Detalles Bibliográficos
Autores principales: Wang, Youcheng, Yao, Yajun, Ma, Yazhe, He, Shanqing, Yang, Mei, Cao, Zhen, Liudi, Shiwen, Fu, Yuntao, Chen, Huiyu, Wang, Xi, Huang, Congxin, Zhao, Qingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724246/
https://www.ncbi.nlm.nih.gov/pubmed/36483596
http://dx.doi.org/10.7150/ijms.69626

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