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Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study

BACKGROUND: To evaluate the effectiveness of enhanced check to the duration of the central venous catheters associated bloodstream infections (CABSIs), and the impact on infection rates. METHODS: A before-after, real-world study in six adult intensive care units was conducted. All adult patients who...

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Autores principales: Lv, Yu, Huang, Xiaobo, Xiang, Qian, Yang, Qin, Chen, Jin, Cai, Minhong, Wang, Pingping, Jia, Ping, Wang, Hui, Xie, Caixia, Li, Luting, Zhang, Dingding, Wei, Daoqiong, Wu, Jiayu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724293/
https://www.ncbi.nlm.nih.gov/pubmed/36474305
http://dx.doi.org/10.1186/s13756-022-01190-z
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author Lv, Yu
Huang, Xiaobo
Xiang, Qian
Yang, Qin
Chen, Jin
Cai, Minhong
Wang, Pingping
Jia, Ping
Wang, Hui
Xie, Caixia
Li, Luting
Zhang, Dingding
Wei, Daoqiong
Wu, Jiayu
author_facet Lv, Yu
Huang, Xiaobo
Xiang, Qian
Yang, Qin
Chen, Jin
Cai, Minhong
Wang, Pingping
Jia, Ping
Wang, Hui
Xie, Caixia
Li, Luting
Zhang, Dingding
Wei, Daoqiong
Wu, Jiayu
author_sort Lv, Yu
collection PubMed
description BACKGROUND: To evaluate the effectiveness of enhanced check to the duration of the central venous catheters associated bloodstream infections (CABSIs), and the impact on infection rates. METHODS: A before-after, real-world study in six adult intensive care units was conducted. All adult patients who had only one central venous catheter were included during two consecutive periods. The intervention period, added cross-check that all patients with central venous catheter (CVC) need to be performed, and included nurses' checks for insertion practices and doctors' checks for maintenance practices. Propensity scores matching were used to account for potential confounding, and restricted cubic spline was served as visualizing the CABSI risk. RESULTS: A total of 2906 patients with 26,157 CVC-days were analyzed. After intervention, the density incidence of CABSI decreased from 10.24 to 6.33/1,000 CVC-days (P < 0.001), and the acute period of rapid increase in CABSI risk was shortened, 6.5 to 5 days for femoral-vein catheterization and 7 to 5.5 days for subclavian-vein catheterization. For jugular-vein catheterization, the acute onset period disappeared. CONCLUSION: Enhanced check during the first 7 calendar days after CVC insertion shortens the duration of the CABSI acute phase and tends to decrease CABSI rate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13756-022-01190-z.
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spelling pubmed-97242932022-12-07 Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study Lv, Yu Huang, Xiaobo Xiang, Qian Yang, Qin Chen, Jin Cai, Minhong Wang, Pingping Jia, Ping Wang, Hui Xie, Caixia Li, Luting Zhang, Dingding Wei, Daoqiong Wu, Jiayu Antimicrob Resist Infect Control Research BACKGROUND: To evaluate the effectiveness of enhanced check to the duration of the central venous catheters associated bloodstream infections (CABSIs), and the impact on infection rates. METHODS: A before-after, real-world study in six adult intensive care units was conducted. All adult patients who had only one central venous catheter were included during two consecutive periods. The intervention period, added cross-check that all patients with central venous catheter (CVC) need to be performed, and included nurses' checks for insertion practices and doctors' checks for maintenance practices. Propensity scores matching were used to account for potential confounding, and restricted cubic spline was served as visualizing the CABSI risk. RESULTS: A total of 2906 patients with 26,157 CVC-days were analyzed. After intervention, the density incidence of CABSI decreased from 10.24 to 6.33/1,000 CVC-days (P < 0.001), and the acute period of rapid increase in CABSI risk was shortened, 6.5 to 5 days for femoral-vein catheterization and 7 to 5.5 days for subclavian-vein catheterization. For jugular-vein catheterization, the acute onset period disappeared. CONCLUSION: Enhanced check during the first 7 calendar days after CVC insertion shortens the duration of the CABSI acute phase and tends to decrease CABSI rate. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13756-022-01190-z. BioMed Central 2022-12-06 /pmc/articles/PMC9724293/ /pubmed/36474305 http://dx.doi.org/10.1186/s13756-022-01190-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Lv, Yu
Huang, Xiaobo
Xiang, Qian
Yang, Qin
Chen, Jin
Cai, Minhong
Wang, Pingping
Jia, Ping
Wang, Hui
Xie, Caixia
Li, Luting
Zhang, Dingding
Wei, Daoqiong
Wu, Jiayu
Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title_full Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title_fullStr Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title_full_unstemmed Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title_short Effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
title_sort effectiveness of enhanced check during acute phase to reduce central venous catheters-associated bloodstream infections: a before-after, real-world study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724293/
https://www.ncbi.nlm.nih.gov/pubmed/36474305
http://dx.doi.org/10.1186/s13756-022-01190-z
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