A functional loop between YTH domain family protein YTHDF3 mediated m(6)A modification and phosphofructokinase PFKL in glycolysis of hepatocellular carcinoma

BACKGROUND & AIMS: N(6)-methyladenosine (m(6)A) modification plays a critical role in progression of hepatocellular carcinoma (HCC), and aerobic glycolysis is a hallmark of cancer including HCC. However, the role of YTHDF3, one member of the core readers of the m(6)A pathway, in aerobic glycolys...

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Detalles Bibliográficos
Autores principales: Zhou, Rong, Ni, Wen, Qin, Chao, Zhou, Yunxia, Li, Yuqing, Huo, Jianping, Bian, Lijuan, Zhou, Aijun, Li, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724358/
https://www.ncbi.nlm.nih.gov/pubmed/36471428
http://dx.doi.org/10.1186/s13046-022-02538-4

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