Tissue plasminogen activator with prolonged dwell time effectively evacuates pleural effusions

OBJECTIVES: Fibrinolytic therapy can be effective for management of complex pleural effusions. Tissue plasminogen activator (tPA, 10 mg) and deoxyribonuclease (DNAse) every 12 h with a dwell time of one hour is a common strategy based on published data. We used a simpler protocol of tPA (4 mg) witho...

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Detalles Bibliográficos
Autores principales: Townsend, Alexandra, Raju, Harsha, Serpa, Krystina A., Pruett, Rachel, Razi, Syed S., Tarrazzi, Francisco A., Tami, Catherine M., Block, Mark I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724361/
https://www.ncbi.nlm.nih.gov/pubmed/36471325
http://dx.doi.org/10.1186/s12890-022-02261-y

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