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Catalase-deficient mice induce aging faster through lysosomal dysfunction
BACKGROUND: Lysosomes are a central hub for cellular metabolism and are involved in the regulation of cell homeostasis through the degradation or recycling of unwanted or dysfunctional organelles through the autophagy pathway. Catalase, a peroxisomal enzyme, plays an important role in cellular antio...
Autores principales: | Dutta, Raghbendra Kumar, Lee, Joon No, Maharjan, Yunash, Park, Channy, Choe, Seong-Kyu, Ho, Ye-Shih, Kwon, Hyug Moo, Park, Raekil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724376/ https://www.ncbi.nlm.nih.gov/pubmed/36474295 http://dx.doi.org/10.1186/s12964-022-00969-2 |
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