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Catalase-deficient mice induce aging faster through lysosomal dysfunction

BACKGROUND: Lysosomes are a central hub for cellular metabolism and are involved in the regulation of cell homeostasis through the degradation or recycling of unwanted or dysfunctional organelles through the autophagy pathway. Catalase, a peroxisomal enzyme, plays an important role in cellular antio...

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Detalles Bibliográficos
Autores principales: Dutta, Raghbendra Kumar, Lee, Joon No, Maharjan, Yunash, Park, Channy, Choe, Seong-Kyu, Ho, Ye-Shih, Kwon, Hyug Moo, Park, Raekil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724376/
https://www.ncbi.nlm.nih.gov/pubmed/36474295
http://dx.doi.org/10.1186/s12964-022-00969-2

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