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Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study

BACKGROUND: Genetic risk factors for chemotherapy-induced peripheral neuropathy (CIPN), a major dose-limiting side-effect of paclitaxel, are not well understood. METHODS: We performed a genome-wide association study (GWAS) in 183 paclitaxel-treated patients to identify genetic loci associated with C...

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Detalles Bibliográficos
Autores principales:	Hooshmand, Kosar, Goldstein, David, Timmins, Hannah C., Li, Tiffany, Harrison, Michelle, Friedlander, Michael L., Lewis, Craig R., Lees, Justin G., Moalem-Taylor, Gila, Guennewig, Boris, Park, Susanna B., Kwok, John B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724416/ https://www.ncbi.nlm.nih.gov/pubmed/36474270 http://dx.doi.org/10.1186/s12967-022-03754-4

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