Pan-cancer surveys indicate cell cycle-related roles of primate-specific genes in tumors and embryonic cerebrum

BACKGROUND: Despite having been extensively studied, it remains largely unclear why humans bear a particularly high risk of cancer. The antagonistic pleiotropy hypothesis predicts that primate-specific genes (PSGs) tend to promote tumorigenesis, while the molecular atavism hypothesis predicts that P...

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Detalles Bibliográficos
Autores principales: Ma, Chenyu, Li, Chunyan, Ma, Huijing, Yu, Daqi, Zhang, Yufei, Zhang, Dan, Su, Tianhan, Wu, Jianmin, Wang, Xiaoyue, Zhang, Li, Chen, Chun-Long, Zhang, Yong E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724437/
https://www.ncbi.nlm.nih.gov/pubmed/36474250
http://dx.doi.org/10.1186/s13059-022-02821-9

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