Macrophage M1 polarization mediated via the IL-6/STAT3 pathway contributes to apical periodontitis induced by Porphyromonas gingivalis

OBJECTIVE: To investigate the involvement of IL-6/STAT3 signaling pathway activation in macrophage polarization and bone destruction related to apical periodontitis (AP) stimulated by Porphyromonas gingivalis. METHODOLOGY: Macrophage polarization, IL-6/STAT3 expression, and the presence of P. gingiv...

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Detalles Bibliográficos
Autores principales: Chen, Xuan, Dou, Jinge, Fu, Zhuohui, Qiu, Yang, Zou, Ling, Huang, Dingming, Tan, Xuelian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade De Odontologia De Bauru - USP 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724497/
https://www.ncbi.nlm.nih.gov/pubmed/36417596
http://dx.doi.org/10.1590/1678-7757-2022-0316

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