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DABCO-promoted highly diastereo- and regioselective construction of C-3 functionalized spirooxindoles via [3 + 2] cycloaddition of 2-aryl/heteroarylidene-1H-indene-1,3(2H)-diones with N-2,2,2-trifluoroethylisatin ketimines at ambient conditions

The application of 2-aryl/heteroarylidene-1H-indene-1,3(2H)-dione as an activated olefin source in the DABCO-catalyzed [3 + 2] cycloaddition with N-2,2,2-trifluoroethylisatin ketimines has been disclosed. This highly efficient 1,3-dipolar cycloaddition reaction offered a variety of trifluoro methyl...

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Detalles Bibliográficos
Autores principales: Prasad, Madavi S., Bharani, Sankar, Sharief, Syed Mastan, Ravi, Mudavath, Sivaprakash, Murugesan, Borah, Biplob, Chowhan, L. Raju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724611/
https://www.ncbi.nlm.nih.gov/pubmed/36540219
http://dx.doi.org/10.1039/d2ra07141j

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