Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report

Endothelial Growth Factor Receptor (EGFR) mutations are frequently found among NSCLC patients. Second-generation Tyrosine Kinase Inhibitor (TKI) Afatinib is frequently used in this population of patients achieving better results than cytotoxic chemotherapy in terms of survival and progression. Afati...

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Autores principales: Ramos, German E., Caglevic, Christian, Bulnes, Juan F., Panay, Sergio E., Zapata, Mario I., Daniele, Andrés J., Rodríguez, Manuel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724619/
https://www.ncbi.nlm.nih.gov/pubmed/36483627
http://dx.doi.org/10.3389/fcvm.2022.1060813
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author Ramos, German E.
Caglevic, Christian
Bulnes, Juan F.
Panay, Sergio E.
Zapata, Mario I.
Daniele, Andrés J.
Rodríguez, Manuel E.
author_facet Ramos, German E.
Caglevic, Christian
Bulnes, Juan F.
Panay, Sergio E.
Zapata, Mario I.
Daniele, Andrés J.
Rodríguez, Manuel E.
author_sort Ramos, German E.
collection PubMed
description Endothelial Growth Factor Receptor (EGFR) mutations are frequently found among NSCLC patients. Second-generation Tyrosine Kinase Inhibitor (TKI) Afatinib is frequently used in this population of patients achieving better results than cytotoxic chemotherapy in terms of survival and progression. Afatinib-related cardiotoxicity has been rarely reported. Here we comment on a clinical case of a Takotsubo Cardiomyopathy Afatinib-induced in an NSCLC patient.
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spelling pubmed-97246192022-12-07 Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report Ramos, German E. Caglevic, Christian Bulnes, Juan F. Panay, Sergio E. Zapata, Mario I. Daniele, Andrés J. Rodríguez, Manuel E. Front Cardiovasc Med Cardiovascular Medicine Endothelial Growth Factor Receptor (EGFR) mutations are frequently found among NSCLC patients. Second-generation Tyrosine Kinase Inhibitor (TKI) Afatinib is frequently used in this population of patients achieving better results than cytotoxic chemotherapy in terms of survival and progression. Afatinib-related cardiotoxicity has been rarely reported. Here we comment on a clinical case of a Takotsubo Cardiomyopathy Afatinib-induced in an NSCLC patient. Frontiers Media S.A. 2022-11-22 /pmc/articles/PMC9724619/ /pubmed/36483627 http://dx.doi.org/10.3389/fcvm.2022.1060813 Text en Copyright © 2022 Ramos, Caglevic, Bulnes, Panay, Zapata, Daniele and Rodríguez. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Ramos, German E.
Caglevic, Christian
Bulnes, Juan F.
Panay, Sergio E.
Zapata, Mario I.
Daniele, Andrés J.
Rodríguez, Manuel E.
Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title_full Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title_fullStr Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title_full_unstemmed Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title_short Takotsubo cardiomyopathy Afatinib-related in a non-small cell lung cancer patient: Case report
title_sort takotsubo cardiomyopathy afatinib-related in a non-small cell lung cancer patient: case report
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724619/
https://www.ncbi.nlm.nih.gov/pubmed/36483627
http://dx.doi.org/10.3389/fcvm.2022.1060813
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