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Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1

ZBP1 is an interferon‐induced cytosolic nucleic acid sensor that facilitates antiviral responses via RIPK3. Although ZBP1‐mediated programmed cell death is widely described, whether and how it promotes inflammatory signaling is unclear. Here, we report a ZBP1‐induced inflammatory signaling pathway m...

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Detalles Bibliográficos
Autores principales: Peng, Ruoshi, Wang, Chris Kedong, Wang‐Kan, Xuan, Idorn, Manja, Kjær, Majken, Zhou, Felix Y, Fiil, Berthe Katrine, Timmermann, Frederik, Orozco, Susana L, McCarthy, Julia, Leung, Carol S, Lu, Xin, Bagola, Katrin, Rehwinkel, Jan, Oberst, Andrew, Maelfait, Jonathan, Paludan, Søren R, Gyrd‐Hansen, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724671/
https://www.ncbi.nlm.nih.gov/pubmed/36268590
http://dx.doi.org/10.15252/embr.202255839