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Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
ZBP1 is an interferon‐induced cytosolic nucleic acid sensor that facilitates antiviral responses via RIPK3. Although ZBP1‐mediated programmed cell death is widely described, whether and how it promotes inflammatory signaling is unclear. Here, we report a ZBP1‐induced inflammatory signaling pathway m...
Autores principales: | Peng, Ruoshi, Wang, Chris Kedong, Wang‐Kan, Xuan, Idorn, Manja, Kjær, Majken, Zhou, Felix Y, Fiil, Berthe Katrine, Timmermann, Frederik, Orozco, Susana L, McCarthy, Julia, Leung, Carol S, Lu, Xin, Bagola, Katrin, Rehwinkel, Jan, Oberst, Andrew, Maelfait, Jonathan, Paludan, Søren R, Gyrd‐Hansen, Mads |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724671/ https://www.ncbi.nlm.nih.gov/pubmed/36268590 http://dx.doi.org/10.15252/embr.202255839 |
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