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POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart
The establishment of macromolecular complexes by scaffolding proteins is key to the local production of cAMP by anchored adenylyl cyclase (AC) and the subsequent cAMP signaling necessary for cardiac functions. We identify a novel AC scaffold, the Popeye domain‐containing (POPDC) protein. The POPDC f...
Autores principales: | Baldwin, Tanya A, Li, Yong, Marsden, Autumn N, Rinné, Susanne, Garza‐Carbajal, Anibal, Schindler, Roland F R, Zhang, Musi, Garcia, Mia A, Venna, Venugopal Reddy, Decher, Niels, Brand, Thomas, Dessauer, Carmen W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724675/ https://www.ncbi.nlm.nih.gov/pubmed/36254885 http://dx.doi.org/10.15252/embr.202255208 |
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