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POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart

The establishment of macromolecular complexes by scaffolding proteins is key to the local production of cAMP by anchored adenylyl cyclase (AC) and the subsequent cAMP signaling necessary for cardiac functions. We identify a novel AC scaffold, the Popeye domain‐containing (POPDC) protein. The POPDC f...

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Detalles Bibliográficos
Autores principales: Baldwin, Tanya A, Li, Yong, Marsden, Autumn N, Rinné, Susanne, Garza‐Carbajal, Anibal, Schindler, Roland F R, Zhang, Musi, Garcia, Mia A, Venna, Venugopal Reddy, Decher, Niels, Brand, Thomas, Dessauer, Carmen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724675/
https://www.ncbi.nlm.nih.gov/pubmed/36254885
http://dx.doi.org/10.15252/embr.202255208

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