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Quantifying In Situ Structural Stabilities of Human Blood Plasma Proteins Using a Novel Iodination Protein Stability Assay

[Image: see text] Many of the diseases that plague society today are driven by a loss of protein quality. One method to quantify protein quality is to measure the protein folding stability (PFS). Here, we present a novel mass spectrometry (MS)-based approach for PFS measurement, iodination protein s...

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Detalles Bibliográficos
Autores principales: Lin, Hsien-Jung L., James, Isabella, Hyer, Chad D., Haderlie, Connor T., Zackrison, Michael J., Bateman, Tyler M., Berg, Monica, Park, Ji-Sun, Daley, S. Anisha, Zuniga Pina, Nathan R., Tseng, Yi-Jie J., Moody, James D., Price, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724711/
https://www.ncbi.nlm.nih.gov/pubmed/36356215
http://dx.doi.org/10.1021/acs.jproteome.2c00323