Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K(+) channels

A search in the GDC Data Portal revealed 304 documented somatic mutations of the KCNJ3 gene in primary tumors (out of 10.202 cases). Most affected tumor types were carcinomas from uterus, skin and lung, while breast cancer exerted the lowest number of somatic mutations. We focused our research on 15...

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Detalles Bibliográficos
Autores principales: Pelzmann, Brigitte, Hatab, Ahmed, Scheruebel, Susanne, Langthaler, Sonja, Rienmueller, Theresa, Sokolowski, Armin, Gorischek, Astrid, Platzer, Dieter, Zorn-Pauly, Klaus, Jahn, Stephan W., Bauernhofer, Thomas, Schreibmayer, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724741/
https://www.ncbi.nlm.nih.gov/pubmed/36483038
http://dx.doi.org/10.3389/fonc.2022.998907

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