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SR-Mitochondria Crosstalk Shapes Ca Signalling to Impact Pathophenotype in Disease Models Marked by Dysregulated Intracellular Ca Release( )

AIMS: Diastolic Ca release (DCR) from sarcoplasmic reticulum (SR) Ca release channel ryanodine receptor (RyR2) has been linked to multiple cardiac pathologies, but its exact role in shaping divergent cardiac pathologies remains unclear. We hypothesize that the SR-mitochondria interplay contributes t...

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Detalles Bibliográficos
Autores principales:	Tow, Brian D, Deb, Arpita, Neupane, Shraddha, Patel, Shuchi M, Reed, Meagan, Loper, Anna-Beth, Eliseev, Roman A, Knollmann, Björn C, Györke, Sándor, Liu, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724772/ https://www.ncbi.nlm.nih.gov/pubmed/34677619 http://dx.doi.org/10.1093/cvr/cvab324

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