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Exploring the mono-/bistability range of positively autoregulated signaling systems in the presence of competing transcription factor binding sites
Binding of transcription factor (TF) proteins to regulatory DNA sites is key to accurate control of gene expression in response to environmental stimuli. Theoretical modeling of transcription regulation is often focused on a limited set of genes of interest, while binding of the TF to other genomic...
Autores principales: | Gao, Rong, Brokaw, Samantha E., Li, Zeyue, Helfant, Libby J., Wu, Ti, Malik, Muhammad, Stock, Ann M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725139/ https://www.ncbi.nlm.nih.gov/pubmed/36413575 http://dx.doi.org/10.1371/journal.pcbi.1010738 |
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