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Metformin Inducing the Change of Functional and Exhausted Phenotypic Tumor-Infiltrated Lymphocytes and the Correlation with JNK Signal Pathway in Triple-Negative Breast Cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Metformin has been shown to have the potential to inhibit the proliferation of malignant cells. This study aimed to investigate the regulatory effect of metformin on phenotypic tumor-infiltrated lymphocytes (...

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Detalles Bibliográficos
Autores principales: Wang, Ruibin, Li, Yuchen, Zhao, Yanjie, Shi, Feng, Zhou, Quan, Wu, Jiangping, Lyu, Shuzhen, Song, Qingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725923/
https://www.ncbi.nlm.nih.gov/pubmed/36482884
http://dx.doi.org/10.2147/BCTT.S384702