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Catalpol Regulates Oligodendrocyte Regeneration and Remyelination by Activating the GEF-Cdc42/Rac1 Signaling Pathway in EAE Mice

The main obstacle to remyelination in demyelinating diseases, such as multiple sclerosis, is the inability of oligodendrocyte precursor cells (OPCs) to differentiate into mature oligodendrocytes (OLs) in the demyelinating region. Consequently, promoting OL differentiation and myelin remodeling is a...

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Detalles Bibliográficos
Autores principales: Wu, Minghui, Kang, Qi, Kang, Yuezhi, Tong, Yanping, Yang, Tao, Fan, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726264/
https://www.ncbi.nlm.nih.gov/pubmed/36482934
http://dx.doi.org/10.1155/2022/7074157

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