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A case report of multiple extramedullary plasmacytoma of the head and neck

Multiple extramedullary plasmacytoma (EMP) of the head and neck is rare and a definitive first-line treatment has not been established. EMP successively as a benign mass occurring in multiple areas of the head and neck is rare. This report describes an atypical case with EMP occurring in multiple ar...

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Autores principales: Zhang, Jin, Ding, Detao, Sun, Juxing, Zhang, Hui, Dai, YunBing, Li, Xiaoying, Ma, Xu, Li, Xiaoyu, Wu, Yungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726292/
https://www.ncbi.nlm.nih.gov/pubmed/36482521
http://dx.doi.org/10.1097/MD.0000000000032203
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author Zhang, Jin
Ding, Detao
Sun, Juxing
Zhang, Hui
Dai, YunBing
Li, Xiaoying
Ma, Xu
Li, Xiaoyu
Wu, Yungang
author_facet Zhang, Jin
Ding, Detao
Sun, Juxing
Zhang, Hui
Dai, YunBing
Li, Xiaoying
Ma, Xu
Li, Xiaoyu
Wu, Yungang
author_sort Zhang, Jin
collection PubMed
description Multiple extramedullary plasmacytoma (EMP) of the head and neck is rare and a definitive first-line treatment has not been established. EMP successively as a benign mass occurring in multiple areas of the head and neck is rare. This report describes an atypical case with EMP occurring in multiple areas of the head and neck. PATIENT CONCERNS: A 35-year-old woman was admitted due to complaints of sore throat discomfort accompanied by hoarseness. The patient had undergone surgical excision of the thyroid gland and parotid gland excision several years ago. Postoperative pathological examination both indicated EMP. This time, the woman suffered EMP in head and neck who was treated with a simple surgery. DIAGNOSIS: Postoperative pathological examination of the tumor indicated EMP, and histopathological findings revealed the tumor to be a plasmacytoma. Immunopathological examination were consistent with the diagnosis of EMP. INTERVENTIONS: The patient underwent surgical resection without radiotherapy. OUTCOMES: Histopathological and immunopathological examination findings revealed the tumor to be EMP. The patient was recurrence-free and did not progress to multiple myeloma (MM) during 19 months follow-up. LESSONS: Increasing the awareness of EMP of head and neck is warranted. Our case confirmed that surgical excision is beneficial in the treatment of small, localized EMP.
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spelling pubmed-97262922022-12-09 A case report of multiple extramedullary plasmacytoma of the head and neck Zhang, Jin Ding, Detao Sun, Juxing Zhang, Hui Dai, YunBing Li, Xiaoying Ma, Xu Li, Xiaoyu Wu, Yungang Medicine (Baltimore) 5700 Multiple extramedullary plasmacytoma (EMP) of the head and neck is rare and a definitive first-line treatment has not been established. EMP successively as a benign mass occurring in multiple areas of the head and neck is rare. This report describes an atypical case with EMP occurring in multiple areas of the head and neck. PATIENT CONCERNS: A 35-year-old woman was admitted due to complaints of sore throat discomfort accompanied by hoarseness. The patient had undergone surgical excision of the thyroid gland and parotid gland excision several years ago. Postoperative pathological examination both indicated EMP. This time, the woman suffered EMP in head and neck who was treated with a simple surgery. DIAGNOSIS: Postoperative pathological examination of the tumor indicated EMP, and histopathological findings revealed the tumor to be a plasmacytoma. Immunopathological examination were consistent with the diagnosis of EMP. INTERVENTIONS: The patient underwent surgical resection without radiotherapy. OUTCOMES: Histopathological and immunopathological examination findings revealed the tumor to be EMP. The patient was recurrence-free and did not progress to multiple myeloma (MM) during 19 months follow-up. LESSONS: Increasing the awareness of EMP of head and neck is warranted. Our case confirmed that surgical excision is beneficial in the treatment of small, localized EMP. Lippincott Williams & Wilkins 2022-12-02 /pmc/articles/PMC9726292/ /pubmed/36482521 http://dx.doi.org/10.1097/MD.0000000000032203 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5700
Zhang, Jin
Ding, Detao
Sun, Juxing
Zhang, Hui
Dai, YunBing
Li, Xiaoying
Ma, Xu
Li, Xiaoyu
Wu, Yungang
A case report of multiple extramedullary plasmacytoma of the head and neck
title A case report of multiple extramedullary plasmacytoma of the head and neck
title_full A case report of multiple extramedullary plasmacytoma of the head and neck
title_fullStr A case report of multiple extramedullary plasmacytoma of the head and neck
title_full_unstemmed A case report of multiple extramedullary plasmacytoma of the head and neck
title_short A case report of multiple extramedullary plasmacytoma of the head and neck
title_sort case report of multiple extramedullary plasmacytoma of the head and neck
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726292/
https://www.ncbi.nlm.nih.gov/pubmed/36482521
http://dx.doi.org/10.1097/MD.0000000000032203
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