Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels

The congenital Long QT Syndrome (LQTS) is an inherited disorder in which cardiac ventricular repolarization is delayed and predisposes patients to cardiac arrhythmias and sudden cardiac death. LQT1 and LQT5 are LQTS variants caused by mutations in KCNQ1 or KCNE1 genes respectively. KCNQ1 and KCNE1 c...

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Detalles Bibliográficos
Autores principales: Zou, Xinle, Wu, Xiaoan, Sampson, Kevin J., Colecraft, Henry M., Larsson, H. Peter, Kass, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726718/
https://www.ncbi.nlm.nih.gov/pubmed/36505078
http://dx.doi.org/10.3389/fphys.2022.902224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726718/
https://www.ncbi.nlm.nih.gov/pubmed/36505078
http://dx.doi.org/10.3389/fphys.2022.902224

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