Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However, the underlying mechanisms of cardiac complications of this syndrome are not fully understood. This study modeled HGPS using cardiomyocytes (C...

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Detalles Bibliográficos
Autores principales: Monnerat, Gustavo, Kasai-Brunswick, Tais Hanae, Asensi, Karina Dutra, Silva dos Santos, Danubia, Barbosa, Raiana Andrade Quintanilha, Cristina Paccola Mesquita, Fernanda, Calvancanti Albuquerque, Joao Paulo, Raphaela, Pires Ferreira, Wendt, Camila, Miranda, Kildare, Domont, Gilberto Barbosa, Nogueira, Fábio César Sousa, Bastos Carvalho, Adriana, Campos de Carvalho, Antonio Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726722/
https://www.ncbi.nlm.nih.gov/pubmed/36505085
http://dx.doi.org/10.3389/fphys.2022.1007418

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