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Impact of the selective A2(A)R and A2(B)R dual antagonist AB928/etrumadenant on CAR T cell function

BACKGROUND: Chimeric antigen receptor (CAR) T cell therapy has been successfully translated to clinical practice for the treatment of B cell malignancies. The suppressive microenvironment of many malignancies is a bottleneck preventing treatment success of CAR T cells in a broader range of tumours....

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Detalles Bibliográficos
Autores principales:	Seifert, Matthias, Benmebarek, Mohamed-Reda, Briukhovetska, Daria, Märkl, Florian, Dörr, Janina, Cadilha, Bruno L., Jobst, Jakob, Stock, Sophia, Andreu-Sanz, David, Lorenzini, Theo, Grünmeier, Ruth, Oner, Arman, Obeck, Hannah, Majed, Lina, Dhoqina, Dario, Feinendegen, Manouk, Gottschlich, Adrian, Zhang, Jin, Schindler, Ulrike, Endres, Stefan, Kobold, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726885/ https://www.ncbi.nlm.nih.gov/pubmed/36266575 http://dx.doi.org/10.1038/s41416-022-02013-z

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