Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children’s Oncology Group

BACKGROUND: Ewing sarcoma (EWS) is an aggressive sarcoma with no validated molecular biomarkers. We aimed to determine the frequency of STAG2 protein loss by immunohistochemistry (IHC) and whether loss of expression is associated with outcome. METHODS: We performed a retrospective cohort study of pa...

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Detalles Bibliográficos
Autores principales: Shulman, David S., Chen, Sonja, Hall, David, Nag, Anwesha, Thorner, Aaron R., Lessnick, Stephen L., Stegmaier, Kimberly, Janeway, Katherine A., DuBois, Steven G., Krailo, Mark D., Barkauskas, Donald A., Church, Alanna J., Crompton, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726932/
https://www.ncbi.nlm.nih.gov/pubmed/36221002
http://dx.doi.org/10.1038/s41416-022-01977-2

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