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Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling

Recently, we demonstrated that a novel bacterial cytotoxin, the protein MakA which is released by Vibrio cholerae, is a virulence factor, causing killing of Caenorhabditis elegans when the worms are grazing on the bacteria. Studies with mammalian cell cultures in vitro indicated that MakA could affe...

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Detalles Bibliográficos
Autores principales: Toh, Eric, Baryalai, Palwasha, Nadeem, Aftab, Aung, Kyaw Min, Chen, Sa, Persson, Karina, Persson, Jenny L., Uhlin, Bernt Eric, Wai, Sun Nyunt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9726977/
https://www.ncbi.nlm.nih.gov/pubmed/36473840
http://dx.doi.org/10.1038/s41419-022-05480-7