Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology

BACKGROUND: Conventional preclinical models often miss drug toxicities, meaning the harm these drugs pose to humans is only realized in clinical trials or when they make it to market. This has caused the pharmaceutical industry to waste considerable time and resources developing drugs destined to fa...

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Detalles Bibliográficos
Autores principales: Ewart, Lorna, Apostolou, Athanasia, Briggs, Skyler A., Carman, Christopher V., Chaff, Jake T., Heng, Anthony R., Jadalannagari, Sushma, Janardhanan, Jeshina, Jang, Kyung-Jin, Joshipura, Sannidhi R., Kadam, Mahika M., Kanellias, Marianne, Kujala, Ville J., Kulkarni, Gauri, Le, Christopher Y., Lucchesi, Carolina, Manatakis, Dimitris V., Maniar, Kairav K., Quinn, Meaghan E., Ravan, Joseph S., Rizos, Ann Catherine, Sauld, John F. K., Sliz, Josiah D., Tien-Street, William, Trinidad, Dennis Ramos, Velez, James, Wendell, Max, Irrechukwu, Onyi, Mahalingaiah, Prathap Kumar, Ingber, Donald E., Scannell, Jack W., Levner, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727064/
https://www.ncbi.nlm.nih.gov/pubmed/36473994
http://dx.doi.org/10.1038/s43856-022-00209-1

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