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Integrative immune transcriptomic classification improves patient selection for precision immunotherapy in advanced gastro-oesophageal adenocarcinoma
BACKGROUND: Advanced gastro-oesophageal cancer (GEA) treatment has been improved by the introduction of immune checkpoint inhibitors (CPIs), yet identifying predictive biomarkers remains a priority, particularly in patients with a combined positive score (CPS) < 5, where the benefit is less clear...
Autores principales: | Cabeza-Segura, Manuel, Gambardella, Valentina, Gimeno-Valiente, Francisco, Carbonell-Asins, Juan Antonio, Alarcón-Molero, Lorena, González-Vilanova, Arturo, Zuñiga-Trejos, Sheila, Rentero-Garrido, Pilar, Villagrasa, Rosana, Gil, Mireia, Durá, Ana, Richart, Paula, Alonso, Noelia, Huerta, Marisol, Roselló, Susana, Roda, Desamparados, Tarazona, Noelia, Martínez-Ciarpaglini, Carolina, Castillo, Josefa, Cervantes, Andrés, Fleitas, Tania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727124/ https://www.ncbi.nlm.nih.gov/pubmed/36253523 http://dx.doi.org/10.1038/s41416-022-02005-z |
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