Cargando…

Identification of pharmacokinetic markers for safflower injection using a combination of system pharmacology, multicomponent pharmacokinetics, and quantitative proteomics study

Safflower injection (SI), a water-extract preparation from safflower (Carthamus tinctorius L.), has been widely used for the treatment of cardio-cerebrovascular diseases. This work aims to develop an approach for identifying PK markers of cardiovascular herbal medicines using SI as a case study. Fir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Peiying, Ruan, Yijun, Zhong, Chenhui, Teng, Linglin, Ke, Liyuan, Yao, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727182/ https://www.ncbi.nlm.nih.gov/pubmed/36506545 http://dx.doi.org/10.3389/fphar.2022.1062026

Ejemplares similares

Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays
por: Yao, Hong, et al.
Publicado: (2018)

An Integrated Pharmacokinetic Study of an Acanthopanax senticosus Extract Preparation by Combination of Virtual Screening, Systems Pharmacology, and Multi-Component Pharmacokinetics in Rats
por: Shi, Peiying, et al.
Publicado: (2020)

An integrated pharmacokinetic study of Dengzhanxixin injection in rats by combination of multicomponent pharmacokinetics and anti-myocardial ischemic assay
por: Huang, Jianyong, et al.
Publicado: (2019)

Recent Research Progress (2015–2021) and Perspectives on the Pharmacological Effects and Mechanisms of Tanshinone IIA
por: Zhong, Chenhui, et al.
Publicado: (2021)

Chemical composition, pharmacology and pharmacokinetic studies of GuHong injection in the treatment of ischemic stroke
por: Wang, Qiuyue, et al.
Publicado: (2023)

Antidepressant-Like Effects of Coumaroylspermidine Extract From Safflower Injection Residues
por: Li, Shifei, et al.
Publicado: (2020)

Alpinetin: A Review of Its Pharmacology and Pharmacokinetics
por: Zhao, Ge, et al.
Publicado: (2022)

Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction
por: Lu, Jing-Ze, et al.
Publicado: (2021)

A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
por: You, Longtai, et al.
Publicado: (2020)

Jatrorrhizine: A Review of Sources, Pharmacology, Pharmacokinetics and Toxicity
por: Zhong, Furong, et al.
Publicado: (2022)

Oridonin: A Review of Its Pharmacology, Pharmacokinetics and Toxicity
por: Li, Xiang, et al.
Publicado: (2021)

The pharmacology, pharmacokinetics, and toxicity of spinosin: A mini review
por: Kuang, Xiaolan, et al.
Publicado: (2022)

Advances in Chemical Constituents, Clinical Applications, Pharmacology, Pharmacokinetics and Toxicology of Erigeron breviscapus
por: Wu, Ruixia, et al.
Publicado: (2021)

Toxicology and Pharmacokinetics Study of Intradiscal Injection of Simvastatin in Rabbits
por: Huang, Xiaodong, et al.
Publicado: (2021)

First-in-human study to investigate the safety and pharmacokinetics of salvianolic acid A and pharmacokinetic simulation using a physiologically based pharmacokinetic model
por: Chen, Jinliang, et al.
Publicado: (2022)

Comparative Pharmacokinetics of Cinobufacini Capsule and Injection by UPLC-MS/MS
por: Li, Ming, et al.
Publicado: (2022)

Properties, Pharmacology, and Pharmacokinetics of Active Indole and Oxindole Alkaloids in Uncaria Hook
por: Kushida, Hirotaka, et al.
Publicado: (2021)

Biotransformation, Pharmacokinetics, and Pharmacological Activities of Ginsenoside Rd Against Multiple Diseases
por: Li, Jing, et al.
Publicado: (2022)

The pharmacokinetics profiles, pharmacological properties, and toxicological risks of dehydroevodiamine: A review
por: Fu, Shubin, et al.
Publicado: (2022)

Monotropein: A comprehensive review of biosynthesis, physicochemical properties, pharmacokinetics, and pharmacology
por: Wu, Mingquan, et al.
Publicado: (2023)

Biliary excretion and pharmacokinetics of several fluoroquinolones after intravenous injection in rabbits
por: SHIMADA, Sumire, et al.
Publicado: (2023)

Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics
por: Dang, Rui, et al.
Publicado: (2023)

Brain Pharmacokinetics and the Pharmacological Effects on Striatal Neurotransmitter Levels of Pueraria lobata Isoflavonoids in Rat
por: Xiao, Bingxin, et al.
Publicado: (2017)

Traditional Chinese Medicine of Angelicae Pubescentis Radix: A Review of Phytochemistry, Pharmacology and Pharmacokinetics
por: Lu, Yaqi, et al.
Publicado: (2020)

Unraveling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling
por: Yang, Xiaoxia, et al.
Publicado: (2015)

Pharmacokinetics, Safety and Pharmacokinetics/Pharmacodynamics Analysis of Omadacycline in Chinese Healthy Subjects
por: Yang, Haijing, et al.
Publicado: (2022)

A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside
por: Wang, Cheng, et al.
Publicado: (2022)

Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing
por: Chen, Teng-Fei, et al.
Publicado: (2022)

Differences in Multicomponent Pharmacokinetics, Tissue Distribution, and Excretion of Tripterygium Glycosides Tablets in Normal and Adriamycin–Induced Nephrotic Syndrome Rat Models and Correlations With Efficacy and Hepatotoxicity
por: Wu, Wei, et al.
Publicado: (2022)

The Traditional Uses, Phytochemistry, Pharmacokinetics, Pharmacology, Toxicity, and Applications of Corydalis saxicola Bunting: A Review
por: Guo, Yanru, et al.
Publicado: (2022)

Pharmacodynamics, Network Pharmacology, and Pharmacokinetics of Chinese Medicine Formula 9002A in the Treatment of Alzheimer’s Disease
por: Tang, Chunlan, et al.
Publicado: (2022)

Acori Tatarinowii Rhizoma: A comprehensive review of its chemical composition, pharmacology, pharmacokinetics and toxicity
por: Wen, Jianxia, et al.
Publicado: (2023)

Local Irradiation Modulates the Pharmacokinetics of Metabolites in 5-Fluorouracil—Radiotherapy–Pharmacokinetics Phenomenon
por: Liu, Ju-Han, et al.
Publicado: (2020)

UPLC-MS/MS Technology for the Quantitative Methodology and Pharmacokinetic Analysis of Voxtalisib in Rat Plasma
por: Li, Qingqing, et al.
Publicado: (2022)

Pharmacokinetics, Immunogenicity and Safety Study for SHR-1309 Injection and Perjeta® in Healthy Chinese Male Volunteers
por: Cui, Yingzi, et al.
Publicado: (2021)

A Comprehensive Review on the Chemical Properties, Plant Sources, Pharmacological Activities, Pharmacokinetic and Toxicological Characteristics of Tetrahydropalmatine
por: Du, Qinyun, et al.
Publicado: (2022)

Physiologic and pharmacokinetic changes in pregnancy
por: Costantine, Maged M.
Publicado: (2014)

“Quantitative Pharmacology: An introduction to integrative pharmacokinetic-pharmacodynamic analysis”
por: Lowe, P J
Publicado: (2012)

Pharmacokinetic assessment of vancomycin in critically ill patients and nephrotoxicity prediction using individualized pharmacokinetic parameters
por: Ghasemiyeh, Parisa, et al.
Publicado: (2022)

A Comprehensive Review of the Chemistry, Pharmacokinetics, Pharmacology, Clinical Applications, Adverse Events, and Quality Control of Indigo Naturalis
por: Sun, Quan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r5o7ge436ftbhvge6640uch1j1