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IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway
Granzymes comprise a group of proteases involved in the killing of infected or cancerous cells by the immune system. Although best studied in T cells and natural killer (NK) cells, they are also expressed in some innate immune cells. Granzymes B and C are encoded in the mouse chymase locus that also...
Autores principales: | Phair, Iain R., Sumoreeah, Megan C., Scott, Niamh, Spinelli, Laura, Arthur, J. Simon C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727205/ https://www.ncbi.nlm.nih.gov/pubmed/36342273 http://dx.doi.org/10.1042/BSR20221165 |
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