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IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway

Granzymes comprise a group of proteases involved in the killing of infected or cancerous cells by the immune system. Although best studied in T cells and natural killer (NK) cells, they are also expressed in some innate immune cells. Granzymes B and C are encoded in the mouse chymase locus that also...

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Detalles Bibliográficos
Autores principales: Phair, Iain R., Sumoreeah, Megan C., Scott, Niamh, Spinelli, Laura, Arthur, J. Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9727205/
https://www.ncbi.nlm.nih.gov/pubmed/36342273
http://dx.doi.org/10.1042/BSR20221165

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